Provenance
Every research output on PepFit is traceable to its original source. No proprietary black boxes — full source trail, evidence grading, and methodology disclosure.
PubMed / MEDLINE
National Library of Medicine · NIH
Primary biomedical literature database. Human clinical trials and systematic reviews.
ClinicalTrials.gov
U.S. National Institutes of Health
Registry of publicly and privately supported clinical studies conducted around the world.
OpenAlex
OurResearch
Open catalog of scholarly works, authors, institutions, and research outputs.
Europe PMC
European Bioinformatics Institute
Life sciences literature database covering PubMed Central and additional European repositories.
openFDA
U.S. Food & Drug Administration
Open access to FDA datasets including adverse events, drug labels, and enforcement reports.
Strong human clinical trial evidence
RCTs, large prospective cohorts, meta-analyses
Good animal or early human evidence
Phase I/II trials, controlled animal studies
In vitro or limited animal evidence
Cell culture, small animal models
Theoretical / mechanistic hypothesis only
Pathway inference, computational models
Insufficient or conflicting evidence
Contradictory studies, no primary data
GRADE Framework
Grading of Recommendations, Assessment, Development and Evaluations — evidence quality system
PRISMA
Preferred Reporting Items for Systematic Reviews and Meta-Analyses
Cochrane Reviews
Gold standard systematic reviews for health interventions
CONSORT
Consolidated Standards of Reporting Trials
PepFit is a research intelligence platform. All outputs are sourced from publicly available scientific literature and require clinician review before any clinical consideration. No dosages, prescriptions, or medical advice are provided.